Journal of psychosomatic research
April 1, 2025
Mengting Zhu, Samuel Yeung-Shan Wong, Claire Chenwen Zhong et al.
13 citations
A network meta-analysis of 68 studies with 5,339 participants compared different mindfulness-based interventions for chronic pain. Mindfulness-based stress reduction showed the strongest evidence for reducing pain intensity and depression, with moderate to high certainty. Mindfulness-oriented recovery enhancement was most effective for improving physical function, though the evidence was low certainty. An 8-week course with weekly 90- to 120-minute sessions appeared optimal for addressing pain, physical function, and depression. These findings support the use of mindfulness-based interventions in chronic pain management and help inform evidence-based guidelines.
Journal of psychosomatic research
July 5, 2025
Ema Štánerová, Veronika Zelenayová, Jakub Rajčáni
8 citations
Mindfulness interventions during active cancer treatment moderately improve quality of life and reduce depression and anxiety. A meta-analysis of controlled clinical trials found moderate effects on quality of life (12 studies, 1124 participants), depression (19 studies, 1586 participants), and anxiety (20 studies, 1542 participants), though with considerable variation across studies. Effectiveness differed by intervention type but not by cancer diagnosis. The overall quality of evidence was low due to unexplained heterogeneity and risk of bias. The findings underscore the need to examine sources of variation and improve methodological transparency in future research.
Journal of psychosomatic research
February 1, 2025
Ana Esteves Ferreira, Paulo Reis-Pina
3 citations
A systematic review of six studies involving 140 patients, most with cancer, found that psychedelic-assisted therapy, particularly with psilocybin, enhances spirituality, mystical experiences, and spiritual well-being in people with life-threatening illnesses. Spiritual well-being improved in all studies that measured it, and mystical experiences were linked to spiritual gains in one study. The evidence comes from studies with a high risk of bias, all conducted in the United States. The review highlights the potential of this therapy to address unmet spiritual needs in palliative care, but calls for more research on how it works and how clinicians can safely guide patients through treatment.
Journal of psychosomatic research
May 1, 2025
Chuntana Reangsing, Sasinun Punsuwun, Sarah Oerther
2 citations
A meta-analysis of 25 randomized controlled trials involving 2,263 cancer patients found that mindfulness-based interventions moderately improve sleep quality (effect size g = 0.598). Participants' mean age was 53.70 years, and most were male. Funding source and timing of outcome measurement influenced the effect size. No adverse effects were reported. Mindfulness-based interventions are a viable complementary treatment for sleep problems in cancer patients.