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PLoS Biology

ISSN 1544-9173

2 papers in the library · 66 citations · publishing 2015-2026

Papers

Illegal Drugs Laws: Clearing a 50-Year-Old Obstacle to Research

PLoS Biology January 27, 2015 David Nutt 66 citations

The United Nations drug control conventions from 1960 and 1971, along with later additions, have inadvertently created major restrictions on medical and life sciences research. These conventions need revision to allow neuroscience to advance without hindrance and to support innovation in treatments for brain disorders. In the interim, local changes like the United Kingdom reclassifying cannabis from Schedule 1 to Schedule 2 should be implemented to enable appropriate medical research development.

Sequential neural dynamics underlie unconscious integration and conscious perception of visual stimuli

PLoS Biology July 6, 2026 Maëlan Q. Menétrey, Michael H. Herzog, David Pascucci

In the Sequential Metacontrast (SQM) paradigm, later visual stimuli alter the perception of earlier ones, indicating that conscious perception can follow extended unconscious processing. Using EEG recordings in humans, researchers identified two distinct neural activity stages: an early occipital pattern around 200 milliseconds after the initial vernier, linked to unconscious processing, and a later centro-parietal pattern between 400 and 600 milliseconds after SQM onset, associated with the integrated percept and behavioral report. The transition between these patterns marks the shift from unconscious encoding of individual visual stimuli to their integrated conscious percept.