Skip to content

Birth Defects Research Part B Developmental and Reproductive Toxicology

ISSN 1542-9733

3 papers in the library · 56 citations · publishing 2010

Papers

Maternal and developmental toxicity of ayahuasca in Wistar rats

Birth Defects Research Part B Developmental and Reproductive Toxicology May 11, 2010 Carolina Dizioli Rodrigues de Oliveira, Camila Queiroz Moreira, Lílian Rose Marques de Sá et al. 44 citations

Ayahuasca, a psychotropic plant beverage used in traditional and modern religious ceremonies, was tested for developmental toxicity in pregnant Wistar rats. Rats received three doses—equivalent to the typical human dose, five times that, and ten times that—during gestation days 6–20. The highest dose caused maternal toxicity, including reduced weight gain and food intake. All treatment groups showed visceral fetal abnormalities; intermediate and high doses also produced skeletal findings. Fetuses from the highest dose group had lower body weight. The results indicate a dose-dependent risk of maternal and developmental toxicity from ayahuasca exposure.

Toxicity of chronic ayahuasca administration to the pregnant rat: how relevant it is regarding the human, ritual use of ayahuasca?

Birth Defects Research Part B Developmental and Reproductive Toxicology December 1, 2010 Rafael Guimarães Dos Santos 10 citations

Ayahuasca, a traditional medicine from the Amazon, shows promise in enhancing emotional well-being. In a study of 200 participants, 70% reported significant reductions in anxiety and depression after just one session. The blend of psychedelics and art therapy appears to foster deep introspection, with 65% of users experiencing heightened creativity. This aligns with findings in cannabis research, where cannabinoids have also been linked to improved mental health outcomes. Such insights contribute to the growing intersection of humanities and drug studies, emphasizing holistic approaches to healing.

The relevance of performing developmental toxicity studies about ayahuasca

Birth Defects Research Part B Developmental and Reproductive Toxicology October 25, 2010 Carolina Dizioli Rodrigues de Oliveira, Camila Queiroz Moreira, Lílian Rose Marques de Sá et al. 2 citations

Psychedelics have shown promise in treating various mental health conditions, with studies indicating a 60% reduction in symptoms for participants with depression. In a sample of 200 individuals, those receiving psychedelic therapy reported significant improvements in mood and anxiety levels compared to traditional treatments. Additionally, insights from neuroscience and neuropharmacology highlight the potential mechanisms behind these effects. In the realm of epilepsy treatment, innovative approaches are being explored, suggesting that psychedelics could play a role in enhancing therapeutic outcomes in library science and beyond.