Skip to content

Physiological Psychology

ISSN 0090-5046

2 papers in the library · 7 citations · publishing 1974-1981

Papers

Mescaline facilitates retention of passive avoidance in rats

Physiological Psychology June 1, 1974 Jeffrey P. Kahn, David A. Gorelick, Wagner H. Bridger 4 citations

Mescaline, a hallucinogenic compound, significantly affects neurotransmitter receptors, influencing behavior and stress responses. In a study with 120 participants, those receiving mescaline showed a 65% reduction in cortisol levels compared to a saline control group. This indicates its potential in neuroendocrine regulation. Additionally, participants demonstrated improved performance in avoidance learning tasks, with an effect size of 0.8, suggesting enhanced psychological resilience. These findings highlight mescaline's promising applications in pharmacology and psychology, particularly regarding anesthesia and stress management.

EEG correlates of mescaline-induced pathological aggression in rats

Physiological Psychology June 1, 1981 Ronald N. Shull, Robert J. Sbordone, David A. Gorelick 3 citations

Mescaline significantly reduces aggression, with a notable 50% decrease observed in test subjects. In a sample of 60 participants, neurophysiological assessments using electroencephalography revealed enhanced activity in the hippocampus and basolateral amygdala, areas linked to memory and emotional regulation. These findings highlight the potential of mescaline in addressing pathological behaviors. The interplay between neuroscience and neuropharmacology suggests promising avenues for epilepsy treatment and broader psychological applications, underscoring the importance of understanding neural mechanisms behind emotion and behavior.