Epileptic seizures have long been linked to religion, especially through the idea of spirit possession. This report presents five cases in which seizures were first blamed on Voodoo spirit possession, and it examines this attribution within the framework of Voodoo beliefs.
In cats pretreated with nonconvulsant doses of pentetrazol or caffeine, a spiking focus induced by topical mescaline appeared earlier, with more frequent and irregular spikes, and in some caffeine-pretreated animals short spike discharges reminiscent of focal seizures were observed. The mescaline spikes altered free amino acid levels throughout the neocortex differently in pretreated versus untreated animals. Glycine increased significantly with either pretreatment; GABA increased significantly only with pentetrazol; alanine increased and arginine decreased only with pentetrazol. In untreated animals, glutamic acid, GABA, and alanine decreased.