Amanita Muscaria and Pantherina – Benefit or Danger? Danger Isoxazole Containing Amanita, Present Situation and Prospects for the Legality of It in Europe
E. Alexandrova, M. Vishnevskii
Emerging Trends in Drugs Addictions and Health December 1, 2025 DOI: 10.1016/j.etdah.2025.100191 via OpenAlex
Summary
AI-generated from the abstractThe rising popularity of red fly agaric over the past decade has brought both benefits and harms. While these mushrooms offer therapeutic potential for somatic and mental illnesses, independent macrodosing and combining them with other entheogens, particularly with Panther fly agaric, significantly increases the risk of hospitalization and death. A graph of hospitalization frequency from 2023-2025 is presented, along with tables of dangerous combinations and a list of side effects from microdosing. The authors conclude that uncontrolled macrodose use, especially in combination with other entheogens, can lead to dangerous outcomes.
Study at a glance
| Characteristics | Review with field studies and data analysis Peer reviewed |
|---|---|
| Population | Volunteers and patients hospitalized with fly agaric poisoning |
| Keywords | Principle of legality Political science Superpower Law and economics |
| Key finding | Uncontrolled macrodosing of red and panther fly agaric, especially when combined with other entheogens, can lead to dangerous outcomes including hospitalization and death. |
Abstract
The popularity of the red fly agaric in the past 10 years has led not only to a positive impact on the inhabitants of Europe and Asia, but also to a number of hospitalizations and even deaths. Independent macrodosing and combination with other entheogens is especially dangerous. Based on the available literature, as well as independent field studies on volunteers, as well as police and hospitals data. Tables of the most dangerous combinations of Red and Panther fly agaric with other plant and chemical entheogens were compiled. A graph of the frequency of hospitalization of patients with poisoning with substances of red and panther fly agaric for 2023-2025 is presented. A list of side effects of red and panther fly agaric during microdosing has been compiled. Despite the enormous benefits of red and panther fly agarics in the treatment of somatic and mental diseases, the uncontrolled use of fly agaric macrodoses, and especially their combination with various other entheogens, can lead to a dangerous outcome.