Amanita Muscaria and Pantherina – Benefit or Danger? Danger Isoxazole Containing Amanita, Present Situation and Prospects for the Legality of It in Europe
Emerging Trends in Drugs Addictions and Health December 1, 2025 E. Alexandrova, M. Vishnevskii
The rising popularity of red fly agaric over the past decade has brought both benefits and harms. While these mushrooms offer therapeutic potential for somatic and mental illnesses, independent macrodosing and combining them with other entheogens, particularly with Panther fly agaric, significantly increases the risk of hospitalization and death. A graph of hospitalization frequency from 2023-2025 is presented, along with tables of dangerous combinations and a list of side effects from microdosing. The authors conclude that uncontrolled macrodose use, especially in combination with other entheogens, can lead to dangerous outcomes.