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Impact of meditation training on the default mode network during a restful state

Véronique A. Taylor, Véronique Daneault, Joshua A. Grant, Geneviève Scavone, Estelle Breton, Sébastien Roffe-Vidal, Jérôme Courtemanche, Anaïs Lavarenne, Guillaume Marrelec, Habib Benali, Mario Beauregard

Social Cognitive and Affective Neuroscience March 24, 2012 DOI: 10.1093/scan/nsr087 via OpenAlex

Summary

AI-generated from the abstract

Experienced meditators with over 1000 hours of training show weaker functional connectivity between default mode network (DMN) regions involved in self-referential processing and emotional appraisal compared to beginners with no prior experience. They also show increased connectivity between certain DMN regions, such as the dorso-medial prefrontal cortex and right inferior parietal lobule. These resting-state functional connectivity changes suggest that extensive meditation training may strengthen present-moment awareness by altering how core DMN regions communicate, even when not actively meditating.

Study at a glance

Characteristics Cross-sectional study Peer reviewed
Sample size 24
Population 13 experienced meditators (over 1000 h of training) and 11 beginner meditators (no prior experience, trained for 1 week)
Intervention Mindfulness meditation
Topics Default mode network Meditation
Keywords Resting State FMRI Functional connectivity
Citations 317
Key finding Experienced meditators had weaker functional connectivity between DMN regions involved in self-referential processing and emotional appraisal, and increased connectivity between certain other DMN regions, compared to beginners.

Abstract

Mindfulness meditation has been shown to promote emotional stability. Moreover, during the processing of aversive and self-referential stimuli, mindful awareness is associated with reduced medial prefrontal cortex (MPFC) activity, a central default mode network (DMN) component. However, it remains unclear whether mindfulness practice influences functional connectivity between DMN regions and, if so, whether such impact persists beyond a state of meditation. Consequently, this study examined the effect of extensive mindfulness training on functional connectivity within the DMN during a restful state. Resting-state data were collected from 13 experienced meditators (with over 1000 h of training) and 11 beginner meditators (with no prior experience, trained for 1 week before the study) using functional magnetic resonance imaging (fMRI). Pairwise correlations and partial correlations were computed between DMN seed regions' time courses and were compared between groups utilizing a Bayesian sampling scheme. Relative to beginners, experienced meditators had weaker functional connectivity between DMN regions involved in self-referential processing and emotional appraisal. In addition, experienced meditators had increased connectivity between certain DMN regions (e.g. dorso-medial PFC and right inferior parietal lobule), compared to beginner meditators. These findings suggest that meditation training leads to functional connectivity changes between core DMN regions possibly reflecting strengthened present-moment awareness.

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