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Uso da ayahuasca no tratamento da depressão

Robenilson Diniz Alves, Epifanio Fernandes da Silva, Maria Loyse da Silva Fernandes, José Jorde Canuto da Silva, Joezilda Sousa Silvestre

RCMOS - Revista Científica Multidisciplinar O Saber November 22, 2021 DOI: 10.51473/rcmos.v1i11.2021.178

Summary

AI-generated from the abstract

Ayahuasca, a tea made from Banisteriopsis caapi vine and Psychotria viridis leaves used in religious rituals like Santo Daime, shows promise for treating depression. A literature review of Portuguese and English articles examined its pharmacological effects in trials and pre-clinical studies. The tea contains bioactive compounds, beta-carbolines and DMT, that interact synergistically to alter perception and emotions. The research found a significant increase in serotonin but did not demonstrate a constant and effective pharmacological effect as a therapeutic. The tests were consistent, indicating the need for more research into ayahuasca's proper interactions to ensure safety and efficacy before widespread treatment use.

Study at a glance

Characteristics Literature review Peer reviewed
Intervention Ayahuasca tea
Key finding Ayahuasca showed promising but inconsistent pharmacological effects for treating depression, with a significant increase in serotonin but not a constant therapeutic effect.

Abstract

Depression is a chronic psychiatric illness that causes deep sadness and a strong feeling of hopelessness. In this sense, new therapies are being approached. Ayahuasca tea is an example, a drink made from the vine of the Banisteriopsis caapi.and the leaves of Psycotria viridis often used in religious rituals such as santo-daime, and which has also been shown to be effective in the treatment of depression and other mental disorders. The study investigates findings about the use of the plant in the treatment of depression. The work starts from a literature review collected mainly by articles in Portuguese and English, aimed at an analysis of the pharmacological effects highlighted in trials and pre-clinical studies. The results provide a range of promising data on the use of drinking for the treatment of depression. Standing out for containing bioactive compounds such as Betacarboline and Dimethyltryptamine (DMT) that interact synergistically, causing changes in the perception of reality and emotions. The research revealed a significant increase in serotonin in the highly acquired, it did not express a constant and effective pharmacological effect as a therapeutic. The tests were very consistent, implying the need for more research into the proper interactions of ayahuasca, in order to guarantee the safety and efficacy and thus spread the treatment in the near future.

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