Psilocybin und Psilocin, zwei psychotrope Wirkstoffe aus mexikanischen Rauschpilzen

Helvetica Chimica Acta  – January 01, 1959

Source: OpenAlex

Summary

The active principles of the Mexican hallucinogenic fungus *Psilocybe mexicana* have been isolated and crystallized. This breakthrough in Chemistry identified psilocybin and psilocin, crucial for Psychedelics and Drug Studies. Psilocybin comprises 0.2 to 0.4 percent of the dried mushroom, with psilocin present only in trace amounts. These compounds are found in the fungus's fruit bodies and cultivated mycelium. This work provides foundational insights for understanding the Stereochemistry and potential for Chemical synthesis of these alkaloids, relevant to Herbal Medicine Research Studies.

Abstract

Abstract The psychotropically active principles of the Mexican hallucinogenic fungus Psilocybe maxicana H EIM have been isolated and obtained in crystalline form. The two new substances, which have been called psilocybin and psilocin , are present in the fruit bodies, the artificially cultivated mycelium and in the sclerotia. The dried mushroom contains 0.2 to 0.4 per cent psilocybin. Psilocin is present, at the most, in trace amounts only.

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