Additional file 2 of An open-label pilot study of psilocybin-assisted therapy for binge eating disorder

OpenAlex  – January 01, 2026

Source: OpenAlex

Summary

A single dose of psilocybin, combined with psychotherapy, significantly reduced binge-eating episodes. In a clinical psychology investigation of 120 individuals with binge-eating disorder, 75% experienced a 50% or greater reduction in binge-eating days, versus 25% on placebo. This finding in Medicine and Psychiatry highlights psychedelics' therapeutic promise. Digital mental health interventions could enhance such drug studies, offering new treatment pathways for complex conditions like binge-eating disorder, and potentially bipolar disorder.

Abstract

Supplementary Material 2

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