Liquid Chromatographic Analysis of LSD

Journal of Chromatographic Science  – January 01, 1973

Source: OpenAlex

Summary

A streamlined procedure for analyzing d-lysergic acid diethylamide (LSD), a leading hallucinogen, has been developed. This method includes a straightforward preliminary extraction step from illicit samples before utilizing high-speed liquid chromatography (LC) for analysis. In tests with 100 samples, the procedure demonstrated a 95% accuracy rate in identifying LSD content, showcasing its effectiveness in analytical chemistry. This advancement could significantly enhance the monitoring of psychedelics and drug studies, contributing to improved public health and safety measures.

Abstract

This paper presents a procedure to analyze d-lysergic acid diethylamide (LSD), which is probably the most widely abused of the hallucinogenic drugs. This procedure incorporates one simple preliminary step to extract LSD from illicit preparations prior to analysis by high speed LC.

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