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Real-world effectiveness and safety of intranasal esketamine for treatment-resistant depression: data from the enTRD registry

Maximilian Preiß, Valentin Popper, Luna Helene Charlotte Faber, Tg Baumgartner, Philip Miguel Baberis-Martinez, Edda Pjrek, Gregor Gryglewski, Lucie Bartova, Siegfried Kasper, Dan Rujescu, Lukas Pezawas

European Psychiatry June 23, 2026 DOI: 10.1192/j.eurpsy.2026.12234 via OpenAlex

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Study at a glance

Characteristics Observational Peer reviewed
Population Patients with TRD from the enTRD registry
Keywords Nasal administration Action physics Onset of action Adverse effect Anesthesia
Key finding Real-world data from the enTRD registry show effectiveness and safety of intranasal esketamine for TRD.

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