Investigations into the polymorphic properties of N,N-dimethyltryptamine by X-ray diffraction and differential scanning calorimetry
Microchemical Journal March 20, 2013 Alain Gaujac, James L. Ford, Nicola M. Dempster et al. 10 citations
N,N-dimethyltryptamine (DMT) may exist in at least two polymorphic forms, explaining the wide variation in reported melting points (38–40 °C to 73–74 °C). Using X-ray powder diffraction and differential scanning calorimetry, including fast scan DSC, on DMT extracted from Mimosa tenuiflora bark or synthesized in the lab, two polymorphs were identified: Form I melts at 57–58 °C and Form II at 45–46 °C, with respective enthalpies of 91.9 ± 2.4 J g⁻¹ and 98.3 ± 2.8 J g⁻¹. Form II converts to Form I during standard DSC, but conversion is prevented at fast scanning rates (100 °C min⁻¹).