Department of General Surgery, Second Xiangya Hospital, Central South University, No. 139, Renmin Middle Road, Furong District, Changsha, Hunan, China. zhouhui.17@csu.edu.cn.
3 papers in the library · 60 citations · publishing 2022-2025
A Chinese translation of the Multidimensional Assessment of Interoceptive Awareness, Version 2 (MAIA-2) was developed and tested in 627 participants. Exploratory factor analysis yielded a 7-factor model after removing 6 items, and confirmatory factor analysis showed good model fit. The total scale had a Cronbach's alpha of 0.822, with subscale alphas ranging from 0.656 to 0.838. Convergent validity was supported by correlations with the Five-Facet Mindfulness Questionnaire (r = −0.342 to 0.535), and discriminant validity by negative correlations with trait anxiety (r = −0.352 to −0.080). The Chinese version is a valid and reliable tool for assessing interoceptive awareness in Chinese populations.
Adding explicit mindfulness instruction to standard Tai Chi Chuan (TCC) training improves beginners' mental and physical health more than TCC alone. In a randomized trial with 119 healthy college students new to TCC, those who received a 10-week Mindfulness-enhanced Tai Chi Chuan (MTCC) program showed significantly greater gains in mindfulness, lower anxiety and stress, and better health- and skill-related physical fitness compared with a standard TCC group. No difference in depression was found between the two groups. The findings suggest that MTCC offers additional mental health benefits while also improving physical fitness, making it a useful intervention for beginners.
Postoperative depression reduces quality of life in breast cancer patients. Esketamine alleviates depressive symptoms by inhibiting TREK-1 potassium channel protein expression, which enhances GABA neurotransmitter release and improves hippocampal neuron activity. In vitro overexpression of TREK-1 reversed these effects. Analysis of data from 54 female breast cancer patients who had surgery between 2019 and 2023, divided into experimental and control groups based on esketamine treatment, along with transcriptomic sequencing of rat hippocampal neurons, identified potassium ion-related pathways and TREK-1 as a key regulatory gene. Esketamine's inhibition of TREK-1 channels and promotion of hippocampal neuron activity suggest a novel therapeutic strategy for postoperative depression in breast cancer patients.