Use of esketamine for tracheoscopic drug injection: a randomized controlled trial.
Frontiers in medicine January 1, 2024 Xiaoming Zhao, Zhendong Zhou, Zhenhua Li et al. 3 citations
In elderly patients undergoing bronchoscopy and lavage under general anesthesia, esketamine maintains more stable intraoperative blood pressure and shortens recovery time compared to sufentanil. A randomized controlled trial of 100 patients aged 60 years or older compared esketamine (0.3 mg/kg) with sufentanil (0.2 μg/kg) during anesthesia induction. The esketamine group had higher blood pressure at multiple time points during the operation and more stable blood pressure overall, though heart rate and oxygen saturation did not differ between groups. Blood pressure and heart rate fluctuated significantly after laryngeal mask insertion in the esketamine group but not in the sufentanil group. Esketamine may enhance hemodynamic stability and reduce hypotension in this population.