Identification of 2C-B in Hair by UHPLC-HRMS/MS. A Real Forensic Case.
Toxics July 15, 2021 José Manuel Matey, Adrián López-fernández, Carmen García-ruiz et al. 7 citations
A reanalysis of hair from a former polydrug consumer, charged with a crime against public health in Spain, positively detected and identified 2C-B, a new psychoactive substance. Using liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS/MS) with a universal and simpler pretreatment method, the technique enabled selective detection of 2C-B at very low concentrations. The approach demonstrates that advanced analytical methods can identify emerging hallucinogens like 2C-B in forensic hair samples, expanding possibilities for detecting substances of different chemical structures.