Forensic Chemistry
April 8, 2022
Cátia Esteves, Elena M. M. de Redrojo, José Luis Manjón et al.
19 citations
A non-destructive method using FTIR-ATR spectroscopy combined with OPLS-DA chemometric analysis can distinguish hallucinogenic mushrooms from edible and toxic species, even though specific psilocybin or psilocin bands were not identified. The technique successfully separated hallucinogenic mushrooms from others, making it a promising initial screening tool for forensic identification of seized samples. The study analyzed 64 mushroom samples from various genera, including hallucinogenic, edible, and toxic species.
Forensic science international
December 1, 2021
J M Matey, Gemma Montalvo, Carmen García-ruiz et al.
19 citations
Among people who test positive for ketamine, polyconsumption of other drugs and new psychoactive substances (NPS) is common. Reanalyzing hair samples from ten former cases—all defendants accused of crimes against public health—using high-resolution mass spectrometry (UHPLC-HRMS/MS) with a methanolic incubation extraction detected additional NPS not found in the original gas chromatography-mass spectrometry (GC-MS) analysis. The additional substances included other arylcyclohexylamines (deschloroketamine, 3-MeO-PCP, methoxetamine) and cathinones (methylmetcathinone, N-ethyl-pentylone). The new method demonstrated its benefits for NPS prevalence studies.
Journal of analytical toxicology
February 14, 2022
J M Matey, Adrián López-fernández, Carmen García-ruiz et al.
13 citations
Analyzing hair and other biological samples for drugs like methoxetamine requires highly selective and sensitive methods. Traditional target analysis using gas chromatography-mass spectrometry can be complex and less sensitive. Reanalyzing samples from a former case of a polydrug consumer in Spain, five metabolites of methoxetamine were tentatively detected using liquid chromatography coupled to high-resolution mass spectrometry (LC-HR-MS-MS). This method, combined with simpler pretreatment, allowed faster and more sensitive analysis than the traditional approach, demonstrating its utility for detecting low concentrations of new psychoactive substances.
Toxics
July 15, 2021
José Manuel Matey, Adrián López-fernández, Carmen García-ruiz et al.
7 citations
A reanalysis of hair from a former polydrug consumer, charged with a crime against public health in Spain, positively detected and identified 2C-B, a new psychoactive substance. Using liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS/MS) with a universal and simpler pretreatment method, the technique enabled selective detection of 2C-B at very low concentrations. The approach demonstrates that advanced analytical methods can identify emerging hallucinogens like 2C-B in forensic hair samples, expanding possibilities for detecting substances of different chemical structures.