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Josephine Kithinji

a Poisons Information Centre, Centre for Pediatrics , Medical Center - University of Freiburg , Germany.

1 paper in the library · 22 citations · publishing 2017

Papers

Bad trip due to 25I-NBOMe: a case report from the EU project SPICE II plus.

Clinical toxicology (Philadelphia, Pa.) September 1, 2017 Maren Hermanns-Clausen, Verena Angerer, Josephine Kithinji et al. 22 citations

A 42-year-old man accidentally ingested 25I-NBOMe, a potent hallucinogenic drug, after taking a sip of pediatric analgesic syrup that had been refilled with a self-made solution of the drug in ethanol. Within 30 minutes he became restless, and in the emergency department he showed dilated pupils, heavy sweating, disorientation, agitation, and later severe agitation, coenesthesia, and complex hallucinations. Blood tests at admission detected 25I-NBOMe (34 ng/mL), its metabolite 2C-I (12 ng/mL), and 25I-NBOH (<1 ng/mL). The syrup contained 2800 μg/mL of 25I-NBOMe. Symptoms resolved after six hours without complications. The presence of 2C-I 50 minutes after intake suggests rapid metabolic breakdown of 25I-NBOMe via first-pass metabolism.