Pharmacological activity of salvinorin A, the major component of Salvia divinorum.
Pharmacological reports : PR January 1, 2011 Joanna Listos, Alicja Merska, Sylwia Fidecka 52 citations
Salvinorin A, the active compound in the hallucinogenic plant Salvia divinorum (magic mint), produces hallucinogenic, antinociceptive (pain-relieving), and antidepressant-like behavioral effects in animals. The compound also shows addictive properties. Its mechanisms of action remain unclear or not well recognized. The paper reviews these behavioral effects and the legal status of the plant and its derivatives. Given the rising recreational use of Salvia divinorum, compiling pharmacological data on salvinorin A is important.