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Jason Nan

Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, Guava Building, Room 130, La Jolla, CA, 92093, United States, 1 6086092291.

2 papers in the library · 15 citations · publishing 2024-2025

Papers

Modulation of Posterior Default Mode Network Activity During Interoceptive Attention and Relation to Mindfulness.

Biological psychiatry global open science November 1, 2024 Dhakshin Ramanathan, Jason Nan, Gillian Grennan et al. 10 citations

Consistency of response times during a breath-monitoring task, measured with electroencephalography in 324 people aged 15 to 91, correlates with attentive performance on an exteroceptive inhibitory control task. On-task alpha band activity (8-12 Hz) was greater than at rest. Low-consistency and longer breath responses were associated with elevated brain activity, particularly in posterior default mode network (pDMN) regions. pDMN activity was inversely linked with functional connectivity to frontal networks during the task but not at rest, suggesting frontal networks regulate pDMN activity during interoceptive attention. Greater pDMN activity in the precuneus was linked to lower subjective mindfulness and was adaptively modulated by task difficulty. Elevated pDMN alpha activity serves as an objective neural marker for low-consistency responding during interoceptive breath attention.

Breath-Focused Mindfulness and Compassion Training in Parent-Child Dyads: Pilot Intervention Study.

JMIR formative research July 17, 2025 Satish Jaiswal, Jason Nan, Seth Dizon et al. 5 citations

A pilot study tested a parent-child digital mindfulness and compassion training app called Cooperative Compassion (CoCo) with 24 families. After 30 sessions over three months, the program was feasible, with 80% of families completing most sessions. Children showed no significant improvement in depression scores but did demonstrate faster processing on an emotion task. Parents experienced significant reductions in stress, anxiety, and depression that lasted at three months, and their mindfulness gains correlated with stress relief. Brain recordings during a breathing task revealed reduced default mode network activity after training, suggesting less mind-wandering and better focus. The results support larger, randomized trials.