Consciousness and cognition
March 1, 2024
Nicholas K Canby, Jared Lindahl, Willoughby B Britton et al.
11 citations
Experiences like mystical states, non-dual awareness, selflessness, and ego dissolution are increasingly studied in meditation and psychedelic research, but their definitions and measures often overlap and lack precision, especially regarding pathological experiences. In a survey of 386 people who reported an experience involving a loss of self or self-boundaries, researchers used statistical and qualitative methods to identify 16 distinct characteristics of such experiences. These included different types of changes in sense of self, accompanying phenomena, and cognitive or emotional responses. The results provide a more specific model for measuring and describing these experiences across contexts like meditation, psychedelics, and psychopathology.
PloS one
January 1, 2025
Nicholas K Canby, Elizabeth A Cosby, Roman Palitsky et al.
10 citations
Childhood trauma and PTSD symptoms are linked to worse depression outcomes and more meditation-related adverse effects in mindfulness-based programs. Across two clinical trials, total childhood trauma and childhood sexual abuse consistently predicted poorer depression outcomes. Childhood sexual abuse also predicted dropout in one study. Multiple forms of trauma and PTSD symptoms predicted meditation-related side effects, while total trauma, emotional abuse, and subclinical PTSD predicted lasting adverse effects. These findings suggest that trauma-sensitive modifications, safety monitoring, screening, and provider education are needed when implementing mindfulness programs for depression.
International review of psychiatry (Abingdon, England)
December 1, 2024
Roman Palitsky, Nicholas K Canby, Nicholas T Van Dam et al.
6 citations
Research on adverse effects (AEs) of psychedelics has been limited, leading to underspecified profiles and potential undercounting. This article argues that meditation-related AE research, which shares phenomenological and contextual features with psychedelic AEs, offers valuable insights. An integrative review of both fields is presented, recommending that meditation AEs serve as a comparator condition. The authors propose adopting detailed, comprehensive, user-informed, impact-based, standardized, unbiased, and representative measures of AEs, along with examining factors that influence their impacts and trajectories, to advance psychedelic AE research.