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Jayaram Thimmapuram

WellSpan Health, York, PA, United States.

3 papers in the library · 36 citations · publishing 2023-2024

Papers

Impact of Heartfulness meditation practice on anxiety, perceived stress, well-being, and telomere length.

Frontiers in psychology January 1, 2023 Mansee Thakur, Yogesh Patil, Sanjana T Philip et al. 27 citations

A 3-month randomized trial with 100 healthy adults aged 18-24 found that practicing Heartfulness meditation significantly reduced cortisol levels and anxiety, while increasing well-being and mindfulness as measured by standard questionnaires. Perceived stress decreased but not significantly. Telomere length correlated negatively with cortisol and positively with well-being, suggesting meditation may slow cellular aging. The authors conclude Heartfulness meditation can improve mental health and affect telomere length, though larger studies are needed to confirm.

Effect of Heartfulness meditation based integrative therapy on infertility outcomes: A retrospective case series evaluation.

Journal of Ayurveda and integrative medicine January 1, 2023 Snehal Deshpande, Kamlesh D Patel, Tejal Parulkar et al. 7 citations

In India, infertility carries social stigma that often prevents couples from seeking support, increasing psychological distress. A retrospective series evaluated a Heartfulness-based integrative therapy combining a 5-day lifestyle workshop and online meditation sessions among 54 couples (mean female age 30.74, male age 34.03). Of these, 15 couples had male infertility, 16 female infertility, 5 both, and 18 unexplained infertility. 24 couples conceived: 18 naturally, five through assisted reproductive technology, and one spontaneous abortion. The program appeared beneficial for those who followed it as prescribed, suggesting Heartfulness meditation may support fertility outcomes, though causal relationships require future randomized controlled trials.

Effect of a Web-Based Heartfulness Program on the Mental Well-Being, Biomarkers, and Gene Expression Profile of Health Care Students: Randomized Controlled Trial.

JMIR bioinformatics and biotechnology December 16, 2024 Jayaram Thimmapuram, Kamlesh D Patel, Deepti Bhatt et al. 2 citations

A 12-week Heartfulness meditation program reduced perceived stress by 17.35% and depression, anxiety, and stress scores by 27.14% among health care students, while a control group showed no significant changes. Dehydroepiandrosterone sulfate (DHEA-S) levels increased significantly by 20.27% in the meditation group, and interleukin-6 (IL-6) levels decreased in both groups. Gene expression analysis identified 875 upregulated and 1,539 downregulated genes in the meditation group compared to baseline, and 292 upregulated and 1,180 downregulated genes compared to the control group after the intervention. These findings suggest Heartfulness meditation improves mental well-being and alters stress-related biomarkers and gene expression profiles.