Dephosphorylation of Psilocybin to Psilocin by Alkaline Phosphatase
Experimental Biology and Medicine January 1, 1961 A. Horita, L. J. Weber 49 citations
The enzyme intestinal phosphatase breaks down psilocybin into psilocin and inorganic phosphate. Psilocin was measured using a colorimetric method and confirmed by paper chromatography. The study describes properties of this enzymatic reaction and considers whether a similar process might occur in living animals.