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Eliza Milliken

Hunter Medical Research Institute

1 paper in the library · 4 citations · publishing 2023

Papers

A review of psilocybin: chemistry, clinical uses and future research directions

Australian Journal of Chemistry May 16, 2023 Eliza Milliken, Peter Galettis, Jenny Martin 4 citations

Classic psychedelics like psilocybin, ketamine, and LSD activate 5HT2A serotonin receptors and produce individualized subjective effects. Public interest in psychedelic medicine is high, but clinical evidence remains limited. Psilocybin and psilocin are tryptophan-based alkaloids found in several mushroom genera. This review covers the current evidence for psilocybin as a clinical medicine, its chemistry, proposed therapeutic mechanism, and future research directions for psilocybin-based therapies.