A Case Report of Psilocybin-induced Psychosis in a Predisposed Patient
Clinical Psychopharmacology and Neuroscience May 21, 2024 S Morris 5 citations
A man with depression, personality disorder traits, and cannabis use developed a psychotic episode with catatonic features and suicidality after several months of heavy psilocybin use. A review of similar published cases shows that psilocybin-induced psychosis typically occurs in people with predisposing risk factors who take high or repeated doses. This pattern warns that psilocybin use carries risks, while reassuring researchers that the much lower doses used in clinical trials for mental illness are safer.