Latent Classes of Lifetime Use of Seven Hallucinogens in the United States
Journal of Psychoactive Drugs August 4, 2025 Meredith C. Meacham, Maha N. Mian, Ralph C. Wang et al. 2 citations
Among U.S. adults who have ever used a hallucinogen, four distinct patterns of lifetime use emerge: a group primarily using psilocybin (16%), a larger group using both LSD and psilocybin (46%), a group mainly using ecstasy (23%), and a group using multiple hallucinogens (15%). Older age is associated with higher odds of being in the LSD/psilocybin class compared with the psilocybin-only class, and non-White participants have higher odds of being in the ecstasy class. These overlapping use patterns suggest that clinical trials and future policies should account for polysubstance hallucinogen experiences.