Comparison and Evaluation of DRI® Methamphetamine, DRI Ecstasy, Abuscreen® ONLINE Amphetamine, and a Modified Abuscreen ONLINE Amphetamine Screening Immunoassays for the Detection of Amphetamine (AMP), Methamphetamine (MTH), 3,4-Methylenedioxyamphetamine (MDA) and 3,4-Methylenedioxymethamphetamine (MDMA) in Human Urine*
Journal of Analytical Toxicology July 1, 2003 Peter Stout, K. L. Klette, Russell Wiegand 21 citations
Four immunoassays for detecting amphetamine, methamphetamine, MDA, and MDMA were tested on about 27,500 human urine samples and 7,000 control samples over eight days. The DRI ecstasy reagent detected about 23% more MDMA-positive samples than the ONLINE reagent and had a confirmation rate near 90%. The modified ONLINE reagent, which included sodium periodate and was calibrated with MDMA, performed poorly, with control failure rates up to 38.3% and no improved MDMA sensitivity. The DRI methamphetamine reagent had a low confirmation rate (6% or less) and frequently gave positive results for samples containing only ephedrine or pseudoephedrine.