Bioassay of Ataractics Against Lethal Action of Mescaline in Mice
Experimental Biology and Medicine July 1, 1958 Nicholas P. Plotnikoff, Helen Washington 7 citations
Chlorpromazine, perphenazine, proclorperazine, promazine, thiopropazate, promethazine, and reserpine effectively block mescaline-induced death in CF1 mice. In contrast, sodium phenobarbital, meprobamate, benactyzine, atropine, hydroxyzine, ethoxybutamoxane, SY-21, diphenylhydantoin, trimethadione, lysergic acid diethylamide, serotonin, amphetamine, morphine, pyrilamine, diphenhydramine, iproniazid, pilocarpine, and arecoline offered no significant protection. The protective effects of the ataractics are suggested to be centrally mediated.