Prolonged Adverse Reactions to LSD in Psychotic Subjects
Archives of General Psychiatry November 1, 1966 Max Fink 40 citations
Prolonged adverse effects from lysergic acid diethylamide (LSD) can last from one week to two years, with about 40% of cases persisting beyond that range. These effects include spontaneous recurrences of the acute LSD experience, persistent psychotic decompensations, depression leading to attempted and completed suicides, and multihabituation. While the experimental LSD experience in medical settings is usually transient—limited to a few hours or a day—the illicit use of the drug has raised concerns about an increasing incidence of persistent psychoses.