Study of a New Schizophrenomimetic Drug—Sernyl
Archives of Neurology And Psychiatry March 1, 1959 Elliot D. Luby 920 citations
Since 1921, researchers have induced temporary psychotic-like states in animals and humans using drugs such as bulbocapnine, mescaline, and LSD-25, aiming to test theories about schizophrenia. Some psychiatrists, like Ebaugh, argue these drug-induced pseudopsychoses differ so markedly from schizophrenia that their relevance to understanding the disorder is limited. Others, like Wikler, contend that for developing causal concepts of behavior, whether the model psychoses resemble schizophrenia is unimportant. The abstract presents this ongoing debate without resolving it.