Chromosomal Damage in Human Leukocytes Induced by Lysergic Acid Diethylamide
Science March 17, 1967 Maimon M. Cohen, Michelle J. Marinello, Nathan Back 199 citations
Lysergic acid diethylamide added to cultured human white blood cells caused a large increase in chromosomal abnormalities. The breaks were not random, with many occurring in chromosome 1. A patient treated with the drug for paranoid schizophrenia over four years also showed similar chromosomal damage.