Anorexia nervosa that emerges alongside adolescent psychosis may function as a 'negative delusion'—not a distortion of the symbolic body but its erasure. Drawing on Lacanian psychoanalytic theory, the paper argues that this erasure stems from a shared structural failure in symbolic integration. Self-starvation can serve as a defense against psychotic threats by negating the body's symbolic dimension within social meaning. The framework has implications for early diagnosis and intervention, identifying a structural configuration in a subset of presentations at the intersection of psychosis and eating restriction, rather than proposing a new diagnostic subtype.
An umbrella review of systematic reviews and meta-analyses on psychedelic microdosing (repeated low doses of LSD or psilocybin) for mood and cognitive effects found that the only statistically significant pooled result was a small decrease in cognitive control, contrary to popular claims of enhancement. Self-reported mood benefits were largely not replicated under placebo-controlled conditions, suggesting expectancy effects. Short-term tolerability was acceptable, but cardiovascular signals and long-term risks remain uncharacterized. The evidence base is limited by high overlap among primary studies and methodological heterogeneity.