Biological research
January 1, 2003
David Rudrauf, Antoine Lutz, Diego Cosmelli et al.
194 citations
Francisco Varela's work on subjectivity and consciousness is reviewed, presenting a view of subjectivity as deeply intertwined with biological and physical roots. His theory of concrete, embodied dynamics, grounded in autonomous systems, posits that biological autonomy defines life and identity as emergent, circular self-producing processes. Embodiment explains how a cognitive self arises from an organism's internal regulation and sensorimotor coupling, with global subjective properties emerging from component interactions and constraining local processes through recursive morphodynamics. Neurophenomenology uses first-person methods to examine experience, creating mutual constraints between biophysical data and subjective accounts, aiming to ground disciplined insight in biophysical emergence. Varela's contribution is framed as a "biophysics of being."
Scientific Reports
October 17, 2017
Constanza Baquedano, Rodrigo C. Vergara, Vladimir Lopez et al.
34 citations
Imagining food can make it feel real, but mindful attention reduces this effect. In one condition, participants were instructed to immerse themselves in food images; in another, they applied mindful attention. Saliva volume and automatic approach bias toward attractive food were measured. Mindful attention reduced saliva volume and automatic approach bias compared to immersion. During immersion, higher saliva volume, subjective realism, and food craving traits were linked to stronger approach bias, while meditation experience was linked to weaker bias. The findings suggest that mindful attention can de-automatize automatic food biases.
European Journal of Neuroscience
December 2, 2019
Constanza Baquedano, Vladimir Lopez, Diego Cosmelli et al.
8 citations
Dereification—viewing mental events as mere representations rather than accurate depictions of reality—is a core feature of mindfulness meditation, contrasted with subjective realism, where one becomes immersed in mental contents. This study examined how mindful versus immersed instructions affect approach-avoidance tendencies toward visual stimuli. Novices and experienced meditators viewed neutral and attractive food images under both states, then performed an approach-avoidance task with behavioral, salivary, EEG, and self-report measures. Approach bias toward attractive food correlated with N2 amplitude (response inhibition), and mindful instruction modulated this bias via N1 amplitude (early attention). Experienced meditators showed less late affective reappraisal during mindfulness, indicated by lower LPP amplitude. Findings suggest mechanisms by which mindfulness-based interventions may help psychiatric conditions.
Frontiers in Psychology
May 24, 2019
Alejandra Vasquez-Rosati, Rodrigo Montefusco-Siegmund, Vladimir Lopez et al.
Negative emotional music slowed reaction times during a task-switching test compared to positive music or silence, but the effect depended on each person's subjective emotional experience. When participants felt hampered by the music, their reaction times were slower and a brain signal called P300 was reduced. The study combined EEG brain monitoring, behavior measures, and detailed interviews about inner experience to show that emotion and cognitive flexibility interact in complex, individual ways.
Frontiers in human neuroscience
January 1, 2018
Gonzalo Boncompte, Diego Cosmelli
The neural signature of conscious perception is debated, with candidates including the P3b, Visual Awareness Negativity (VAN), and early components like P1. Most studies use static images, favoring ventral stream processing. This experiment isolated local motion, a dorsally processed feature, as the consciously perceived content. Using physical equality between Seen and Unseen conditions and minimal contrast differences, a P3b with wide centro-parietal distribution strongly correlated with stimulus detection, with larger magnitude for Seen vs. Unseen conditions consistently at the single subject level. VAN was undetectable, and P1 was absent. A N2pc component appeared in the 200-300 ms window, consistent with high attentional demands. Results extend P3b's role as a content-independent neural correlate of consciousness to visual motion perception.