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Clemens Bauer

2 papers in the library · 89 citations · publishing 2020-2024

Papers

Real-time fMRI neurofeedback reduces auditory hallucinations and modulates resting state connectivity of involved brain regions: Part 2: Default mode network -preliminary evidence

Psychiatry Research January 14, 2020 Clemens Bauer, Kana Okano, Satrajit Ghosh et al. 87 citations

Auditory hallucinations in schizophrenia are linked to overactivity and hyperconnectivity in the default mode network and reduced anticorrelation with the central executive network. Patients were trained with real-time fMRI neurofeedback and meditation strategies to modulate these networks. The intervention reduced default mode network hyperconnectivity and increased anticorrelation between the default mode and central executive networks. Changes in individual default mode network connectivity correlated with reductions in auditory hallucination frequency and severity. This provides the first empirical evidence that meditation-enhanced neurofeedback can directly alter resting state network activity and reduce auditory hallucinations.

ENIGMA-Meditation: Worldwide consortium for neuroscientific investigations of meditation practices

April 8, 2024 Saampras Ganesan, Aki Tsuchiyagaito, Greg J. Siegle et al. 2 citations preprint

Meditation practices, which have been adapted into manualized interventions for conditions like depression, pain, addiction, and anxiety, show therapeutic promise, but their neuroscientific basis remains unclear. Current neuroimaging studies rely on small, heterogeneous datasets that vary in practice types, participant experience, clinical targets, and imaging methods, limiting generalizability and replicability. To address this, the ENIGMA-Meditation consortium was formed as a global collaboration to conduct systematic meta- and mega-analyses of distributed neuroimaging data using standardized methods. This framework aims to improve statistical power and rigorously characterize the neural mechanisms underlying meditation's effects on psychological and cognitive attributes, advancing the field of contemplative neuroscience.