Lysergic Acid Diethylamide: Mutagenic Effects in Drosophila Science September 6, 1968 Luolin S. Browning 29 citations Injection of massive doses of d-lysergic acid diethylamide (LSD) into male fruit flies (Drosophila) significantly increases the number of recessive lethal mutations in their X chromosome. DOI: 10.1126/science.161.3845.1022