Early intervention in psychiatry
June 1, 2019
Barnaby Nelson, Emily Li, David C Cicero et al.
39 citations
The Inventory of Psychotic-Like Anomalous Self-Experiences (IPASE) shows strong construct validity as a self-report measure of minimal self-disturbance. In a sample of 46 participants including ultra-high risk and first-episode psychosis patients and healthy controls, the IPASE correlated very strongly (r = 0.92) with the gold-standard interview measure (EASE). It also correlated strongly with general psychopathology and positive psychotic symptoms, moderately with negative symptoms, and weakly with manic symptoms. The IPASE may serve as a screener but cannot replace the in-depth assessment of minimal self-disturbance, which requires clinical expertise.
Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
August 1, 2025
Vera A Barata, Suzie Lavoie, Łukasz Gawęda et al.
3 citations
Among 43 individuals at ultra-high risk for psychosis, those who later remitted had lower baseline levels of basic self-disturbance than those whose symptoms persisted or who transitioned to psychosis. Basic self-disturbance scores predicted worse clinical outcomes at 12 months. Source monitoring deficits were greater in first-episode psychosis patients than in those at ultra-high risk whose symptoms persisted or transitioned. The findings suggest that high levels of basic self-disturbance may serve as a predictor of poor prognosis in ultra-high risk patients.
Psychological medicine
January 12, 2026
Lawrence Kin-Hei Chung, Thomas J Whitford, Anson Kai Chun Chau et al.
People with schizophrenia who hear voices experience inner speech—the silent, internal monologue—more frequently and with a different character than healthy individuals. Using repeated daily surveys on electronic devices, researchers found that voice-hearers reported more moments of inner speech and higher intensity of evaluative, other people's voices, condensed, and positive inner speech, though not dialogic inner speech. When voice-hearers experienced more intense dialogic, evaluative, other people's, or condensed inner speech, they also reported more severe auditory verbal hallucinations. Negative emotions strengthened the link between evaluative inner speech and hallucination severity. The findings suggest inner speech contributes to voice-hearing and that emotional state may be a target for therapy.