One-Year Outcomes Following Intravenous Ketamine Plus Digital Training Among Patients with Treatment-Resistant Depression
JAMA Network Open May 1, 2023 R. Price, M. Wallace, S. Mathew et al. 9 citations
Automated self-association training may extend the antidepressant effect of a single ketamine infusion beyond one month in people with treatment-resistant depression. This secondary analysis of a randomized clinical trial tested whether a computerized task designed to strengthen positive self-associations could prolong the benefits of ketamine. The results suggest that combining ketamine with this training could help maintain mood improvement for a longer period than ketamine alone.