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Christian A. Webb

5 papers in the library · 12 citations · publishing 2022-2025

Papers

Revealing subgroup-specific mechanisms of change via moderated mediation: A meditation intervention example.

Journal of Consulting and Clinical Psychology September 28, 2023 Christian A. Webb, Matthew J. Hirshberg, Oscar González et al. 6 citations

Mechanisms explaining why meditation training works may differ across patient subgroups. Prior research often collapsed heterogeneous groups, obscuring these differences. Using data from 662 participants, researchers developed a Personalized Advantage Index (PAI) to identify individuals likely to benefit more from a meditation app. A moderated mediation analysis showed that mindfulness acquisition mediated better outcomes only for those with higher PAI scores. This suggests that subgroup-specific mediators should be considered to clarify how psychosocial interventions work and to match individuals to the most beneficial treatment.

Can Psychedelic Use Benefit Meditation Practice? Examining Individual, Psychedelic, and Meditation-Related Factors

medRxiv August 28, 2024 Zishan Jiwani, Simon B. Goldberg, Jack Stroud et al. 3 citations preprint

Most meditators who use psychedelics perceive them as beneficial for their meditation practice. Among 863 regular meditators (practicing at least three times weekly for the past year) who also used psychedelics, machine learning identified four factors most likely to predict this positive perception: greater frequency of psychedelic use, setting intentions before use, higher agreeableness, and having used N,N-Dimethyltryptamine (DMT). The model explained about 27% of the variance. The findings suggest that intentional and personality factors may shape how psychedelics influence meditation, but causality remains unestablished.

Can psychedelic use benefit meditation practice? Examining individual, psychedelic, and meditation-related factors.

PLoS One February 12, 2025 Zishan Jiwani, Simon B. Goldberg, Jack Stroud et al. 1 citation

Most meditators who also use psychedelics report that the drugs improve their meditation practice. In a survey of 863 regular meditators who had used psychedelics, 73.5% said psychedelics positively influenced the quality of their meditation. Machine learning analysis of 53 variables identified the strongest predictors of this perceived benefit: greater frequency of psychedelic use, setting intentions before taking psychedelics, having an agreeable personality, and having used N,N-Dimethyltryptamine (N,N-DMT). The results suggest that individual traits and patterns of use shape whether psychedelics are seen as helpful for meditation, but causality cannot be established from this cross-sectional data.

Ecological Momentary Assessment as a Measure of Intervention Change: Evaluation in 4 Digital Mental Health Trials

October 17, 2023 Christian A. Webb, Lori M. Hilt, Caroline M. Swords et al. 1 citation preprint

Ecological momentary assessment (EMA) measures of rumination are only modestly correlated with conventional self-report measures, especially for change over time, partly due to lower reliability of EMA. Changes in rumination were larger for conventional self-report than EMA. Both types of measures accounted for unique variance in depressive symptom improvement, showing incremental predictive validity. The findings suggest that EMA and conventional self-report provide distinct, clinically meaningful information. Researchers using EMA should consider psychometric properties and the precise construct they intend to capture.

Personalized prediction of response to smartphone-delivered meditation training: A machine learning approach (Preprint)

July 31, 2022 Christian A. Webb, Matthew J. Hirshberg, Richard J. Davidson et al. 1 citation

An algorithm was developed to predict who benefits most from a meditation app. Using data from a randomized controlled trial of a 4-week meditation app versus a control condition in 662 school system employees, a machine learning model created a Personalized Advantage Index (PAI) that estimated each person's expected reduction in distress. The PAI scores significantly predicted which individuals improved more with the app than without. A simpler model using only repetitive negative thinking as a predictor performed similarly well. The algorithm could help individuals make informed decisions about whether a meditation app is right for them.