Chromosomal Abnormalities in Leukocytes from LSD-25 Users
Science July 21, 1967 DOI: 10.1126/science.157.3786.313 via OpenAlex
Summary
AI-generated from the abstractChromosomal abnormalities were significantly more frequent in leukocytes from LSD-25 users (six out of eight) than in nonuser controls (one out of nine). The two users without damage had the lowest estimated average dose. Damaged cells were observed in samples taken between 1 day and 6 months after the last dose.
Study at a glance
| Characteristics | Case-control study Peer reviewed |
|---|---|
| Sample size | 17 |
| Population | LSD-25 users and nonuser controls |
| Intervention | LSD-25 |
| Duration | 1 day to 6 months after last LSD-25 dose |
| Topics | LSD |
| Keywords | Andrology Genetics Molecular biology Physiology |
| Citations | 139 |
| Key finding | LSD-25 users showed a significant increase in chromosomal abnormalities in leukocytes compared to nonuser controls. |
Abstract
A significant increase of chromosomal abnormalities was found in leukocytes from LSD-25 users (six out of eight) compared to nonuser controls (one out of nine). The two LSD-25 users showing no damage reported the lowest estimated average dose. The subjects whose cells showed damage were tested between 1 day and 6 months after their last LSD-25 dose.