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Chromosomal Damage in LSD Users

José Egozcue

JAMA April 15, 1968 DOI: 10.1001/jama.1968.03140160024006 via OpenAlex

Summary

AI-generated from the abstract

People who use LSD have more chromosomal abnormalities in their white blood cells than non-users. Children exposed to LSD before birth also show higher rates of chromosome breakage. However, the amount of drug taken per dose, the number of doses, or the total dosage did not correlate with how often breaks occurred.

Study at a glance

Characteristics Observational study Peer reviewed
Population LSD users and drug-free controls, and children exposed to LSD in utero
Keywords Medicine Internet privacy Medical emergency
Citations 59
Key finding LSD users and children exposed to the drug in utero have higher rates of chromosomal breakage, but the frequency of breaks does not correlate with dosage.

Abstract

An increase of chromosomal abnormalities was found in leukocytes of LSD users compared to drug-free controls. Elevated breakage rates were also found in children exposed to the drug in utero. The data showed no correlation between amount of drug per dose, number of doses, or total dosage and frequency of chromosomal breaks.

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