Multiple Ocular Anomalies Associated With Maternal LSD Ingestion
Calvin Chun-Kit Chan, M. Fishman, P. R. Egbert
Archives of Ophthalmology February 1, 1978 DOI: 10.1001/archopht.1978.03910050150009 via OpenAlex
Summary
AI-generated from the abstractA premature baby girl was born with severe eye malformations—small eyes (microphthalmos), cartilage inside the eye, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia. The mother had taken LSD during the first three months of pregnancy. This is the third reported case linking maternal LSD use to eye defects in the baby. More cases are needed to confirm whether LSD actually causes these malformations.
Study at a glance
| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Premature baby girl |
| Keywords | Microphthalmos Medicine Pregnancy Ingestion Teratology |
| Citations | 46 |
| Key finding | Severe ocular malformations occurred in a premature infant whose mother ingested LSD during the first trimester, representing the third reported case of possible LSD-related eye teratogenesis. |
Abstract
Severe ocular malformations, including microphthalmos, intraocular cartilage, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia, occurred in a premature baby girl. The mother had ingested LSD during the first trimester of pregnancy. To our knowledge, this is the third case reported of ocular teratogenesis associated with maternal LSD ingestion. Further cases must be documented to establish an actual cause and effect relationship between the drug and the induced malformations.