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Optic Disc Anomalies and Maternal Ingestion of LSD

Creig Hoyt

Journal of Pediatric Ophthalmology & Strabismus September 1, 1978 DOI: 10.3928/0191-3913-19780901-06 via OpenAlex

Summary

AI-generated from the abstract

Two infants born to mothers who habitually used LSD during pregnancy each had an isolated bilateral optic disc anomaly, suggesting an early intrauterine insult. The authors propose that LSD may express its teratogenicity in a relatively benign form and stress the need for further investigation into the etiology of optic disc anomalies.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 2
Population Infants born to mothers who habitually used LSD during pregnancy
Keywords Medicine Etiology Pregnancy Ingestion Optic disc
Citations 15
Key finding Two infants exposed to LSD in utero had isolated bilateral optic disc anomalies, suggesting a possible teratogenic effect of LSD.

Abstract

two patients born to others habitually using LSD during pregnancy are described. Each infant had an isolated bilateral optic disc anomaly suggesting an early intrauterine insult. The possibility that LSD may express its teratogenicity in such relative benign fashion is suggested and the importance of further investigations concerning the etiology of disc anomalies is stressed.

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