Oscar G Cabrices

G-Flo Scientific, Miramar, FL CEP 33025, United States.

2 papers in the library · 22 citations · publishing 2021-2024

Papers

Innovative disposable pipette extraction for concurrent analysis of fourteen psychoactive substances in drug users' sweat.

Journal of chromatography. A August 16, 2024 Nayna Cândida Gomes, Oscar G Cabrices, Bruno Spinosa De Martinis 12 citations

A new method using disposable DPX-SCX extraction tips and gas chromatography-mass spectrometry can simultaneously detect and quantify 16 psychoactive substances—including amphetamines, cocaine, fentanyl, and several novel psychoactive substances—in sweat samples collected with laboratory-developed patches. Validation showed quantification limits between 2 and 30 ng per patch and linearity from 2 to 1100 ng per patch. When applied to 30 sweat samples from volunteer drug users, the method detected cocaine, MDMA, nicotine, caffeine, and other compounds, with recovery rates of 72.4% to 97.1%. Sweat is a viable, non-invasive biological matrix for monitoring drug use, particularly in rehabilitation settings.

DOI: 10.1016/j.chroma.2024.465136 Full text Dpx-scx Gc-ms Psychoactive substances Sweat +8

Kinetic profile of N,N-dimethyltryptamine and β-carbolines in saliva and serum after oral administration of ayahuasca in a religious context.

Drug testing and analysis March 1, 2021 Rafael Lanaro, Sueli Moreira Mello, Kelly Francisco da Cunha et al. 10 citations

After consuming ayahuasca, alkaloids such as DMT and β-carbolines reach higher peak concentrations and overall exposure in saliva than in serum, while their mean residence time is 1.5 to 3 times longer in serum. A statistical model suggests that serum concentrations can be predicted from saliva concentrations, though individual variability is large. Saliva offers a fast, noninvasive way to detect these alkaloids and could aid in identifying recreational use of similar compounds that pose intoxication risks.

DOI: 10.1002/dta.2955 Full text Ayahuasca Dimethyltryptamine Saliva Serum +1