BioMed Research International
January 1, 2014
Francesco Saverio Bersani, Ornella Corazza, Gabriella Albano et al.
98 citations
25C-NBOMe, sold online as legal LSD or under names like 'N-bomb' and 'Pandora', is a partial agonist of 5-HT2A receptors that carries a high risk of overdose, with acute toxicity and fatalities reported. It is taken orally, sublingually, nasally, by injection, vaginally, rectally, or smoked, producing effects such as sublingual numbing, stimulation, hallucinations, dissociation, and anxiety. Its use is an emerging phenomenon increased by low-cost online availability, and health professionals should be informed about this trend.
Frontiers in Psychology
April 25, 2025
Antonio Metastasio, Elisabeth Prevete, Sofia Venturini et al.
8 citations
People who took psilocybin without other substances reported lasting increases in emotional sensitivity, empathy, and connection to others, along with deeper insights into their lives and values. The experience also led to profound shifts in behavior, attitudes, and interests, suggesting psilocybin can catalyze personal growth. This qualitative study used phenomenological methods to systematically describe the subjective psychedelic experience, aiming to inform its integration into psychotherapy.
Performance Enhancement & Health
November 1, 2025
Thomas Zandonai, Sofia Venturini, Ornella Corazza
Ketamine and psilocybin may improve recovery and pain management in athletes, potentially enhancing resilience, mood, and cognitive flexibility. However, increasing use among athletes raises safety concerns and challenges for anti-doping regulations. Evidence on long-term effects when combined with exercise is scarce, highlighting the need for further research.
Drug Science Policy and Law
January 1, 2023
Antonio Metastasio, Silvio Mignogna, Riccardo Paci et al.
LSD, when used under therapeutic guidance, enhanced the filmmaking creativity of Federico Fellini by altering his perception of time, space, body, and self. Time in his films flows irregularly with disorienting flashbacks; colors become supernaturally brilliant and detached from objects; sounds emerge independently from visible sources; and human bodies appear deformed, grotesque, and caricatural. The boundaries between dream and reality collapse. These changes made his films so distinctive that the adjective 'felliniesque' was coined.