Ibogaine interferes with the establishment of amphetamine place preference learning.
Experimental and clinical psychopharmacology May 1, 1997 I Moroz, L A Parker, S Siegel 11 citations
A single injection of ibogaine given 24 hours before amphetamine prevented the formation of a conditioned place preference for amphetamine after one or two conditioning trials, but was less effective after four trials. The reduced effectiveness with more trials appears due to tolerance developing to ibogaine.