Journal of Psychopharmacology
July 31, 2024
Roman Palitsky, Deanna M. Kaplan, John Perna et al.
32 citations
A multidisciplinary working group identified 54 potential adverse events that warrant systematic assessment in psychedelic-assisted therapies, finding that existing measurement tools substantially fail to cover these constructs. The group developed recommendations for when and how to assess these adverse events across preparation, dosing, integration, and follow-up phases, and demonstrated a preliminary assessment protocol. The framework addresses the need to capture post-acute dosing adverse events, accounting for both the pharmacotherapy and psychotherapy components of psychedelic-assisted therapy, as well as documented impacts on worldviews and spirituality.
BMC Psychiatry
February 28, 2025
John Perna, Justin Trop, Roman Palitsky et al.
15 citations
A case report describes tensions between legal and underground psychedelic use within therapy training programs, psychiatry, and neo-shamanism. It details how psychiatric interventions like electroconvulsive therapy and energy medicine were used to address prolonged adverse effects from psychedelics. The report urges clinicians to recognize conflicts between psychiatric views of these adverse effects and frameworks in psychedelic communities, which can affect patients' symptoms, decisions, and emotional struggles.
March 5, 2024
Roman Palitsky, Deanna M. Kaplan, John Perna et al.
4 citations
preprint
A multidisciplinary working group identified 53 potential adverse events (AEs) specific to psychedelic-assisted therapies (PATs) that current assessment tools miss. Existing measures cover only a fraction of these constructs. The group recommends new assessment methods—including patient, clinician, and informant reports—and specifies when to measure AEs across preparation, dosing, integration, and follow-up phases. The framework addresses gaps in capturing post-acute dosing effects, including changes in worldview and spirituality, which distinguish PAT from other treatments.