JAMA
August 8, 1966
J. Thomas Ungerleider
61 citations
An analysis of 70 cases of adverse reactions to LSD, taken outside medical or research settings, reveals a wide range of psychiatric side effects, from depressive reactions to full psychotic states. The varied symptoms and patient characteristics underscore the risks associated with non-medical LSD use. Observations from these cases and from community users suggest that widespread use of LSD is a cause for concern.
American Journal of Psychiatry
May 1, 1968
J. Thomas Ungerleider, Duke D. Fisher, Marielle Fuller et al.
59 citations
Comparing 25 people hospitalized after taking LSD with 25 regular users who had no reported difficulties, the study found no clear historical or clinical features that could reliably predict who would have an adverse reaction. The authors suggest that LSD interacts with personality traits such as schizoid tendencies and unstable reality testing in a complex manner, making accurate prediction of individual responses nearly impossible.
American Journal of Psychiatry
September 1, 1968
J. Thomas Ungerleider, Duke D. Fisher, Stephen R. Goldsmith et al.
44 citations
A survey of psychiatrists, psychiatric residents, internists, general practitioners, and psychologists in Los Angeles County counted over 2,000 patients with adverse LSD reactions seen during an 18-month period, which the authors consider a conservative estimate. Despite many clinicians' belief that such reactions were declining, the data show a substantial increase in reported cases from the first six-month period to the third.
JAMA
August 8, 1966
J. Thomas Ungerleider
43 citations
Adverse reactions to lysergic acid diethylamide (LSD) are diverse, with psychiatric side effects ranging from depressive reactions to psychotic states. In 70 cases, LSD was taken outside of medical or therapeutic settings. Observations of these cases and community users raise concern about the drug's widespread use.