Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017–2020: A Review
Journal of Analytical Toxicology April 20, 2022 Amanda L A Mohr, Barry K. Logan, Melissa F. Fogarty et al. 66 citations
A critical review of published case reports from January 2017 through December 2020 identified 1,319 cases of adverse events associated with novel psychoactive substances (NPS), including 378 overdose fatalities, 771 cases requiring clinical treatment or hospitalization, and 170 cases of driving under the influence. The review covers chemistry, pharmacology, user profiles, and clinical symptoms for over 60 NPS, with 50 substances reported for the first time compared to the previous four years. Cases span synthetic cannabinoids, NPS stimulants, hallucinogens, benzodiazepines, and opioids. The findings aim to improve awareness and characterization of emerging international drug threats.