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Acute Leukemia With Ph1-Like Chromosome in an LSD User

Lionel Grossbard

JAMA September 9, 1968 DOI: 10.1001/jama.1968.03140370093024 via OpenAlex

Summary

AI-generated from the abstract

A person who used several hallucinogenic drugs, including LSD, mescaline, marijuana, and amphetamines, developed acute leukemia. The patient's leukemic cells contained a Ph1-like chromosome, a finding rarely reported in acute leukemia or in individuals who have taken LSD. Lymphocytes transformed with phytohemagglutinin did not show chromosome breaks.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population A user of hallucinogenic drugs who developed acute leukemia
Topics LSD Mescaline
Keywords Medicine Hallucinogen Leukemia
Citations 23
Key finding A Ph1-like chromosome was found in the leukemic cells of a hallucinogenic drug user with acute leukemia.

Abstract

Acute leukemia occurred in a user of several hallucinogenic drugs (lysergic acid diethylamide [LSD], mescaline, marihuana, and amphetamines). The leukemic leukocytes of the patient contained a Ph1-like chromosome; lymphocytes transformed with phytohemagglutinin did not show chromosome breaks. A Ph1-like chromosome has only rarely been reported in either acute leukemia or in cultured lymphocytes of individuals ingesting LSD.

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